[实验性寒冷损伤性周围神经病动物模型神经血流神经病理及神经电生理研究]贾健平

【实验性寒冷损伤性周围神经病动物模型神经血流神经病理及神经电生理研究】贾健平.pdfAbstract(cBC)intravellersexposedtorigorous weatherconditions.Since thattimeobservationsoncoldinjuryhavelargelystemmedfromthe exigenciesofwar.ThedevastatingeffectsofcolduponNapoleons troops in the Russian campaign were documented by Larrey.He temperatureswerejustabovefreezing-point.Inthesecondpartofthesestudies,wehaveexaminedthemorphological changesincoldinjuredsciaticnerveatdeferentsurvivingtimes following hypothermic insult.Five groups of 6 to 10Wistarrats,in whichNBFhadbeenmeasuredfollowingcoldinjurytothesciaticnerve in the first part,were used.In this part,a selective conductionblock wasproduced successfullyby twodifferentcoolingparadigms.On thebasis of thesefindings,our conclusions are(l)thereduction of nervebloodflowfollowedbythrombosisformationconfirmsthatcold induces ischaemia;theischaemicchangesofmyelinated fibres indicate that i
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