[经门静脉途径注射同种异体脾细胞对急性移植物抗宿主疾病影响的研究]郭树彬-V2

【经门静脉途径注射同种异体脾细胞对急性移植物抗宿主疾病影响的研究】郭树彬.pdf此论文献给我尊敬的导师 范洪学教授 衷心感谢导师三年来给予我的悉心 指导和无私的帮助！对导师为我所 做的一切在此表示深深的谢意！Review TheRoleofCell-mediatedImmunologicalResponseinthe AcuteGraft-Versus-HostDiseaseafterBoneMarrow Transplantation LIntroduction Bone marrow transplantation has evolvedoveraperiodof50years.Over thepasttwodecadesallogeneicbonemarrowtransplantation(BMT)has becomeaneffectiveandgloballyacceptedtherapy经门静脉途径注射同种异体牌细胞对急性移植物抗宿主疾病影响的研究 cells(W3/25+) that are very potent in induction of lethal GVHD.Lethal GVHDis alsObserved after transfer ofpurified OX8+cells,although these cellsseem tobe much less potent thanW3/25+cells;Similarly,lethalGVHD directed towholeH-2differencesin mice involves predomin
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