[经门静脉途径注射同种异体脾细胞对急性移植物抗宿主疾病影响的研究]郭树彬

【经门静脉途径注射同种异体脾细胞对急性移植物抗宿主疾病影响的研究】郭树彬.pdf此论文献给我尊敬的导师 范洪学教授 衷心感谢导师三年来给予我的悉心 指导和无私的帮助！对导师为我所 做的一切在此表示深深的谢意！经门静脉途径注射同种异体牌细胞对急性移植物抗宿主疾病影响的研究 Review TheRoleofCell-mediatedImmunologicalResponseinthe AcuteGraft-Versus-HostDiseaseafterBoneMarrow Transplantation LIntroduction Bonemarrowtransplantationhasevolvedoveraperiodof50years.Over thepast two decades allogeneicbone marrowtransplantation(BMT)has become anef经门静脉逾径注射同种异体牌细胞对急性移植物抗宿主疾病影响的研究 cells(W3/25+)that are very potent in induction of lethal GVHD.Lethal GVHDisalsoobservedafter transferofpurifiedOX8+cells,althoughthese cellsseemtobemuchlesspotentthanW3/25+cells;Similarly,lethalGVHD directedtowholeH-2differencesinmiceinvolvespredominantlyLy-1+2- cell
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