[激光萤光早期肺癌诊断理论及其实验研究]

【激光萤光早期肺癌诊断理论及其实验研究】.pdfTheoreticalandExperimentalResearchesonDiagnosis and Localization of Early LungCancer byLaser-InducedFluorescence DissertationSubmittedto Zhejiang University inpartialfulfilmentoftherequirement for the degree of Doctor ofEngineering by Zheng Wei Dissertation Supervisor:Professor Lu Zhukang Professor摘要 基于上述的研究分析和我们原有的工作基础,提出用Kr紫激光做激发光源、处理功能的激光荧光肺癌诊断与定位的实验系统。实验验证的结果表明,该系统 能有效地消除自体荧光给诊断带来的影响,大大提高了荧光图像衬比度,实现了消 除假阳性和假阴性误诊的目标。ABSTRACT throughcalibratingtheresponseofthedetectionsystemwiththeknownpowerdensity.We havemeasured the fluence rates in the fresh samples of human lung tissues(including normal and tumoral tissues)invitroirradiatedbythebroadcollimatedbeams of aKr+laser at the 406.415nmaswellasaHe-Nelaserat632.
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