【革兰化阴性菌内毒素诱导人白细胞间素-1白细胞间素-6和肿瘤坏死因子的功能和化学合成类脂A部分】.pdf
Doctoral Dissertation The Induction of Interleukin 1,Interleukin 6 and Tumor Necrosis Factor-byLipopolysaccharideanditsModulation bySyntheticLipid-APartialStructures Ph.D Student:Wang Ming-Hai Institute of Infectious Diseases Zhejiang Medical University Hangzhou,Zhejiang,Peoples Republic of China
activities with the requirement of their chemical structures Among the Lps-mediated regulation of immunnoiogical functions,monocytes/macrophages(Xo/M)play a critical role in the defence ins acainst invadedAmicroorganismS(o)
YATERIALSAND YETHODS pS,lipic A and partial structures.?s of Samonella abortus egu:(S.a.e.?s) was extracted and 4a soteeO Surproooe pouiau wmatoxaa/touud au Aa pe7srand a(o),and was kindly provided by Drade(Borste(compound5o6)s composed ofa bisphosphorylated glucosamine cisaccharice with six