【钙拮抗剂钙调素抑制剂增强抗肿瘤药物毒性研究】何琪杨.pdf
鸣谢 完成毕业论文之际,深为老师和同学们的热情关心和帮助所感动,论文自 始至终,受到薛绍白、张鸿卿二位导师的精心指导,无论从选题、实验及结果 讨论都渗透着二位恩师的心血,他们严勤的治学态度,默默的奉献精神,深为愚 生折服,终生难忘,十分感谢姜兵同学的帮助,没有他提供的抗性细胞株,将使论 文大为逊色,论文的打字,排版工作由胡云英老师完成,她那娴熟的文字处理技 术,使论文大为增色,此外,论文还得到宋平根、李素文、成汝萱、李华、胡云 英,杨中海老师的热情指导和帮助.
Abstract Potentiationof antitumor drugs cytotoxicities and reversalof tumor cellresistant to antitumor drugsare an action of calcium antagonists and calmodulin inhibitors.It was studiedinthisthesiswhetherincreasementofantitumor drugs cytotoxicitiesbynaturalcalmodulininhibitors from plants in contras
The presentthesis confirmed thatnaturalcalmodulin inhibitors from plants have characteristicofpotentiation ofpengyangmycin,adriamycin cytotoxicitiestocellsand reversaloftheresistantcellstoadriamycin.It is avaiabletostudyfurtheritsmechanism.